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April 28, 2004

Supplemental Oxygen and Risk of Surgical Site Infection

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(16):1956. doi:10.1001/jama.291.16.1956-a

To the Editor: Dr Pryor and colleagues1 reported that patients who received 80% inspired oxygen during and 2 hours after abdominal surgery had a significantly higher rate of surgical site infections (SSIs) than did those who received 35% oxygen. Although the authors controlled the concentration of inspired oxygen, they apparently did not consider other crucial factors such as fluid management, temperature, anesthetic management, and pain control. Tissue perfusion, and thus oxygenation, is often inadequate when these variables are not closely monitored and controlled.2

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