Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Pryor and colleagues1 reported that patients who received 80% inspired
oxygen during and 2 hours after abdominal surgery had a significantly higher
rate of surgical site infections (SSIs) than did those who received 35% oxygen.
Although the authors controlled the concentration of inspired oxygen, they
apparently did not consider other crucial factors such as fluid management,
temperature, anesthetic management, and pain control. Tissue perfusion, and
thus oxygenation, is often inadequate when these variables are not closely
monitored and controlled.2
Hopf HW, Hunt TK, Rosen N. Supplemental Oxygen and Risk of Surgical Site Infection. JAMA. 2004;291(16):1956. doi:10.1001/jama.291.16.1956-a