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May 12, 2004

Vitamin Supplementation and Risk of Stroke—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(18):2191-2192. doi:10.1001/jama.291.18.2191-c

In Reply: In response to Dr Aguirre and colleagues, we have analyzed the proportion of patients taking aspirin or other antiplatelet agents in the 2 treatment groups. As would be expected from randomization of a large number of patients, there was no imbalance: 49.85% of those in the high-dose group vs 50.15% of those in the low-dose group were taking these medications at baseline (P = .71), and this did not change during the course of the study.

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