Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Jiang and colleagues1 reported that higher iron stores are an independent
risk factor for type 2 diabetes in healthy women. I am concerned that the
cases had higher serum ferritin levels at the onset, and differed from controls
in other important respects. Compared with controls, cases were more likely
at baseline to have a family history of diabetes, an increased body mass index,
less physical activity, higher levels of C-reactive protein, and substantially
higher levels of insulin and hemoglobin A1c (mean, 6.4%).
Trotter WD. Iron Stores as a Risk Factor for Diabetes in Women. JAMA. 2004;291(20):2428-2429. doi:10.1001/jama.291.20.2428-a