Author Affiliations: Division of Gastroenterology and Nutrition, Children's Hospital Boston, Boston, Mass (Dr Duggan); Child and Adolescent Health and Development, World Health Organization, Geneva, Switzerland (Dr Fontaine); Johns Hopkins Bloomberg School of Public Health, Baltimore, Md (Drs Pierce and Santosham); Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Ga (Dr Glass); Society for Applied Studies, Kolkata, India (Dr Mahalanabis); Clinical Sciences Division, ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh (Dr Alam); and Department of Pediatrics, All India Institute of Medical Sciences, New Delhi (Dr Bhan).
Diarrheal diseases remain important causes of death and morbidity in
developing countries, with an estimated 1.5 billion episodes and 1.5 million
to 2.5 million deaths each year among children younger than 5 years.1- 4 Although
the number of children currently dying from diarrhea continues to be unacceptably
high, it is substantially lower than the 5 million deaths per year estimated
20 years ago.5
Duggan C, Fontaine O, Pierce NF, Glass RI, Mahalanabis D, Alam NH, Bhan MK, Santosham M. Scientific Rationale for a Change in the Composition of Oral Rehydration Solution. JAMA. 2004;291(21):2628–2631. doi:10.1001/jama.291.21.2628