Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Drs Michels and Ekbom1 concluded that severe caloric restriction in humans
may confer protection from invasive breast cancer. I am concerned, however,
that these findings may inadvertently imply that anorexia nervosa can have
health benefits. Anorexia nervosa is a serious illness, with as many as 15.6%
of patients dying from disease-related causes within 21 years of first hospitalization.2
Mao JJ. Risks and Benefits of Severe Caloric Restriction. JAMA. 2004;291(22):2704. doi:10.1001/jama.291.22.2704-a