[Skip to Content]
[Skip to Content Landing]
June 16, 2004

Use and Timing of Radiotherapy in High-Risk Prostate Cancer

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(23):2817. doi:10.1001/jama.291.23.2817-a

To the Editor: Dr Stephenson and colleagues1 reported a 45% 4-year progression-free probability of isolated biochemical recurrence after radical prostatectomy at a median follow-up of 45-months following salvage radiotherapy. Although we concur with the authors that salvage radiotherapy may alter the natural history of prostate cancer in many men with isolated recurrence of prostate-specific antigen (PSA), we disagree with Dr Anscher's conclusion, in his accompanying Editorial,2 that all men with positive surgical margins should receive adjuvant therapy.

First Page Preview View Large
First page PDF preview
First page PDF preview