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June 16, 2004

C-Reactive Protein and Risk of Colon Cancer

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(23):2818-2819. doi:10.1001/jama.291.23.2819-a

To the Editor: Dr Erlinger and colleagues1 reported that plasma CRP levels are higher among individuals who subsequently develop colon cancer. The authors also found that even though smokers had higher CRP levels, this interaction was not associated with an increase in the risk for subsequent development of colon cancer. These findings suggest that the cause of the elevation of CRP was important in determining whether high CRP levels increased the chance for subsequent development of colon cancer.

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