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Health Agencies Update
June 23/30, 2004

Chronic Pain

JAMA. 2004;291(24):2933. doi:10.1001/jama.291.24.2933-a

Deleting specific nerve cells from the nervous system can block chronic pain in dogs, report scientists from the National Institute of Dental and Craniofacial Research, in Bethesda, Md. The cells, C-fiber neurons, can also be deleted from human neurons cultured together in the laboratory, suggesting that the strategy may also work in humans (J Clin Invest. 2004;113:1344-1352).

The research included 8 dogs severely affected by osteoarthritis, cancer-related pain, or both. All of the treated animals became more active and walked with only a slight limp or none at all. None suffered adverse effects.

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