Citations 0
JAMA 100 Years Ago
July 7, 2004


JAMA. 2004;292(1):119. doi:10.1001/jama.292.1.119

Pathology, that is, the study of disease in the broadest sense, has received only limited attention from the point of view of general biology. Problems connected with the evolution of disease, with the significance of pathologic processes in evolution, and others of like nature, seem to occupy but little of the interest of either biologists or pathologists. We have human pathology, veterinary and animal pathology, vegetable pathology, each with its various subdivisions, and each cultivated with great assiduity on account of its practical and economic importance, but general comparative pathology, somewhat after the order of general comparative anatomy, as yet has barely shown signs of development. Perhaps the most important contribution from the little cultivated field is Metchnikoff's well-known comparative study of inflammation, in which he traces some of the principal phenomena of the inflammatory process up through the ascending stages of the animal kingdom. This work has contributed greatly to a broader understanding of the nature and significance of inflammation.