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July 7, 2004

Inflammation and Age-Related Macular Degeneration

JAMA. 2004;292(1):43. doi:10.1001/jama.292.1.43-a

To the Editor: Dr Seddon and colleagues1 reported that C-reactive protein is significantly associated with intermediate and advanced stages of age-related macular degeneration (AMD), independent of established risk factors such as obesity and smoking. The authors concluded that inflammation may have a role in the pathogenesis of AMD and suggested that anti-inflammatory agents might be used in preventing AMD.