To the Editor: Dr Seddon and colleagues1 reported that C-reactive protein is significantly
associated with intermediate and advanced stages of age-related macular degeneration
(AMD), independent of established risk factors such as obesity and smoking.
The authors concluded that inflammation may have a role in the pathogenesis
of AMD and suggested that anti-inflammatory agents might be used in preventing
Penfold PL. Inflammation and Age-Related Macular Degeneration. JAMA. 2004;292(1):43. doi:10.1001/jama.292.1.43-a