[Skip to Content]
[Skip to Content Landing]
Citations 0
July 14, 2004

On-Pump vs Off-Pump Coronary Artery Bypass Grafting—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;292(2):169. doi:10.1001/jama.292.2.169-d

In Reply: In response to Mr Patel, we discussed the conduct of perfusion in considerable detail in the preliminary report from this study,1 which was cited extensively in our current article. We do agree, however, that cardiopulmonary bypass techniques and technologies have recently been the subject of significant innovation, perhaps as a response to the perceived "threat" of off-pump CABG. Low-prime circuits, retrograde autologous priming, coated tubing, and dilutional ultrafiltration have recently demonstrated promise and are techniques and technologies we and others currently use. However, during enrollment for our trial, mini-primed circuits were in an early phase of development. Perfusion techniques in our trial were state of the art at the time and were compared with contemporary techniques for off-pump CABG.