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July 28, 2004

Can Current Treatments for Advanced Non–Small-Cell Lung Cancer Be Improved?

Author Affiliations

Author Affiliations: Division of Hematology-Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern Unversity, Chicago, Ill (Dr Argiris) and Department of Medicine, University of Wisconsin Hospital, Madison (Dr Schiller).

JAMA. 2004;292(4):499-500. doi:10.1001/jama.292.4.499

Lung cancer is a worldwide epidemic primarily caused by tobacco smoking.1 Approximately 1 million new cases of lung cancer are diagnosed each year worldwide, resulting in more than 900 000 deaths.2 Of these, approximately 175 000 new cases and 160 000 deaths occur annually in the United States.3 Unfortunately, late diagnosis of lung cancer is the rule, and no curative therapies exist for metastatic disease. Nevertheless, perceptible progress in the treatment of this disease has been made as the result of painstaking efforts and decades of clinical investigations.