Although Helicobacter pylori infects nearly
half the world's population, most remain asymptomatic, suggesting the existence
of a natural defense against H pylori–associated
peptic ulcer and gastric malignancies. Now, scientists from Japan and the
United States have discovered that a chemical secreted in deeper portions
of the stomach lining may play a role in curbing the bacterium's pathogenic
effects (Science. 2004;305:100-103) .
Stephenson J. Helicobacter pylori. JAMA. 2004;292(11):1294. doi:10.1001/jama.292.11.1294-b