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September 22/29, 2004

Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292(12):1428-1429. doi:10.1001/jama.292.12.1428-b

To the Editor: As an intensive care unit director, I read the study by Dr Merten and colleagues with great interest.1 However, as a clinician caring for outpatients, the possibility of oral bicarbonate therapy is important, particularly with its high oral bioavailability. Providing patients with a pre-procedure regimen of bicarbonate pills plus water followed by the same post-procedure treatment may result in efficacy equal to intravenous therapy, leading to a more rapid discharge from the hospital setting.

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