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September 22/29, 2004

Intravenous Immunoglobulin and Quality of Life

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292(12):1429-1430. doi:10.1001/jama.292.12.1429-a

To the Editor: The clinical review by Dr Dalakas1 underscores that intravenous immunoglobulin (IVIG) is the treatment of choice in Guillain-Barré syndrome (GBS), multifocal motor neuropathy, and chronic inflammatory demyelinating polyneuropathy (CIDP) and that it is useful instead of plasma exchange for management of myasthenia gravis. On the other hand, he stresses the necessity of further studies of dose-finding effects, pharmacoeconomics, and quality of life (QOL) assessments to improve the evidence base for clinical practice.

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