Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: Dr Johansson and colleagues1 contribute valuable information on the natural history
of prostate cancer. However, in my opinion their conclusions are not warranted.
The radical treatments available for this disease involve a significant risk
of adverse effects and, consequently, often result in a decreased quality
of life for patients. Due to widespread use of prostate-specific antigen testing,
overdiagnosis and overtreatment have become significant problems2,3 in
both treatment of indolent tumors and in radical treatment.
Oláno JP. Natural History of Early Localized Prostate Cancer. JAMA. 2004;292(13):1549-1550. doi:10.1001/jama.292.13.1549-b