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October 6, 2004

Fetal Microchimeric Cells and Breast Cancer

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292(13):1552-1553. doi:10.1001/jama.292.13.1552-a

To the Editor: Multiple reproductive factors affect a woman’s lifetime risk of developing breast cancer. Nulliparity confers an increased risk, whereas the total number of births is inversely correlated with cancer risk. The biological mechanisms underlying these relationships have not been fully clarified, although both hormonal and cellular changes are implicated.1

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