Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: Dr Schuit and colleagues1 demonstrated a significant association between estrogen
receptor α gene (ESR1) polymorphisms and increased
risk of myocardial infarction (MI) in postmenopausal women but not in men.
Since Mattila et al2 first found an association
between poor oral health and risk of MI in men, several studies have found
such an association in women as well.3 We have
reported a significant association between ESR1 polymorphisms
and tooth loss in postmenopausal women.4
Taguchi A. Estrogen Receptor α Polymorphisms and the Risk of Myocardial Infarction. JAMA. 2004;292(14):1683-1684. doi:10.1001/jama.292.14.1683-a