Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: First reported by E. L. Keyes
in 1882,1 emphysematous cystitis is a rare
complication of urinary tract infection, characterized by spontaneous gas
formation in the urinary bladder. Patients with cystic fibrosis (CF) have
several risk factors that predispose them to urolithiasis, such as hyperoxaluria,
hypercalciuria, hyperuricosuria, and increased urinary saturation of calcium
oxalate.2,3 Diabetes due to the
pancreatic insufficiency common in CF may further increase risk of urinary
infections and formation of renal stones.2,3 However,
to our knowledge occurrence of emphysematous cystitis has not been reported
in patients with cystic fibrosis. We describe a case of emphysematous cystitis
and renal stones in a patient with cystic fibrosis.
Upadhyay D, Jain M. Emphysematous Cystitis and Renal Stones in Cystic Fibrosis. JAMA. 2004;292(16):1951-1954. doi:10.1001/jama.292.16.1953-b