To the Editor: The review of emerging risk
factors for atherosclerotic vascular disease by Drs Hackam and Anand,1 while describing recent evidence quite well, illustrates
one of the pitfalls of limiting literature searches to relatively recent years.
Had they expanded their search to earlier years, they might have noted articles
describing the discovery of and providing insight into biochemical mechanisms
of processes they reviewed.
Pilgeram L. History of Emerging Vascular Disease Risk Factors. JAMA. 2004;292(17):2086. doi:10.1001/jama.292.17.2086-b