Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: The study by Dr Kreijkamp-Kaspers
and colleagues1 indicates that the daily intake
of soy protein enriched with isoflavones has no role in improving cognitive
function, BMD, and plasma lipid levels in relatively elderly postmenopausal
women. Although this conclusion about the administration of soy isoflavones
appears valid, there is good evidence that soy protein may be effective in
lowering plasma lipid levels. This is supported by the meta-analysis by Anderson
et al2 cited in this article. Most of the studies in this meta-analysis
used far higher daily doses of soy protein than the present study did. Studies
such as that of the “dietary portfolio”3 support
a real benefit of vegetable vs animal protein for the reduction of hypercholesterolemia
and for cardiovascular disease prevention.
Sirtori CR. Isoflavones and Postmenopausal Women. JAMA. 2004;292(19):2338-2339. doi:10.1001/jama.292.19.2336-c