Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: The study by Dr Esposito and
colleagues1 showed positive effects of a program
of lifestyle change and weight loss on erectile function in obese men, but
did not address sleep-disordered breathing, which is associated with both
obesity and erectile dysfunction.2 Given the
high body mass indices of study participants, many may have had sleep apnea.
Weight loss is also known to be effective for treating sleep apnea,3 and a recent study found that treatment of sleep apnea
with nasal continuous positive airway pressure resulted in improved erectile
function.4 Esposito et al showed that the group
of obese men with erectile dysfunction had evidence of abnormal endothelial
function and ab normalities of vascular endothelial function, which have been
described with obstructive sleep apnea.5
Feinsilver SH. Erectile Dysfunction in Obese Men. JAMA. 2004;292(20):2466-2467. doi:10.1001/jama.292.20.2466-d