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November 24, 2004

Erectile Dysfunction in Obese Men—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292(20):2466-2467. doi:10.1001/jama.292.20.2467-b

In Reply: We thank Dr Bursztyn for pointing out the articles describing the effect of low-dose antihypertensive drugs and diet on sexual function in hypertensive overweight patients. The risk of erectile dysfunction is closely linked to the presence of well-recognized risk factors for coronary heart disease. Hypertensive patients are particularly vulnerable to erectile dysfunction as a consequence of both hypertension and the use of antihypertensive medications. The interesting finding that weight loss may counterbalance thiazide-induced erectile dysfunction is particularly welcome in light of recent reappraisal of the use of low-dose diuretics as a primary therapy for hypertension.1

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