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Books, Journals, New Media
December 1, 2004


Author Affiliations

Books, Journals, New Media Section Editor: Harriet S. Meyer, MD, Contributing Editor, JAMA; David H. Morse, MS, University of Southern California, Norris Medical Library, Journal Review Editor.

JAMA. 2004;292(21):2661-2666. doi:10.1001/jama.292.21.2663

The origins of modern psychopharmacology are usually ascribed to the introduction of lithium for the treatment of bipolar disorder in 1949. Some trace the origins of biological psychiatry to Hippocrates, who placed the seat of emotions in the brain, or to Paracelsus, who used medicinals in the treatment of mental disorders. Whatever the genesis of the field, modern clinical psychopharmacology has grown most rapidly since the introduction of antipsychotics in the 1950s and again with the advances in brain research over the past two decades.

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