Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: The study by Dr Habu and colleagues1 suggests that vitamin K2 (menaquinone)
supplementation prevents hepatocellular carcinoma in women with viral cirrhosis
of the liver. Supplementation would be expected to be more beneficial in patients
who have a vitamin K deficiency at the onset of the study, but the vitamin
K status of the patients was not reported.
Piquet M, Hourmand-Ollivier I, Dao T. Vitamin K Deficiency and Hepatocellular Carcinoma. JAMA. 2004;292(21):2580-2581. doi:10.1001/jama.292.21.2580-b