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Medical News and Perspectives
December 8, 2004

Malaria Vaccine Shows Promise

JAMA. 2004;292(22):2703-2704. doi:10.1001/jama.292.22.2703

The largest malaria vaccine efficacy trial ever conducted in Africa has proven that a candidate vaccine is safe in children aged 1 to 4 years and can protect a significant proportion of them against uncomplicated malaria, infection, and severe forms of the disease for at least 6 months.

“This is clearly the best result we’ve ever seen with a candidate malaria vaccine,” said Pedro Alonso, MD, PhD, principal investigator of the study and head of the Center for International Health of the Hospital Clinic at the University of Barcelona, in Spain. “All the results point in the same direction with great consistency and substantial precision. So we’re quite certain not only that the vaccine has been safe and immunogenic but that we’ve seen clear efficacy of this vaccine.”

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