Author Affiliation: Division of Endocrinology,
Metabolism, and Diabetes, Department of Medicine, University of Colorado at
Denver and Health Sciences Center, Aurora.
Individuals seeking to lose weight have many diet choices, ranging
from very low-fat (Ornish) to very high-fat (Atkins). However, despite great
popularity and millions of dollars of sales, good-quality comparative data
on the safety and effectiveness of these diets remain elusive.1,2 The
study by Dansinger et al3 in this issue of JAMA could be the randomized trial many have been waiting
for to help determine which diet works best. Yet, even after considering a
number of important limitations, the primary outcome of weight loss at 1 year
was modest and there was no difference between the low-carbohydrate approach
of Atkins, the high-protein low-glycemic load approach of Sears (the Zone
diet), the very low-fat approach of Ornish, and the low-calorie/portion-size
approach of Weight Watchers.
Eckel RH. The Dietary Approach to ObesityIs It the Diet or the Disorder?. JAMA. 2005;293(1):96-97. doi:10.1001/jama.293.1.96