Author Affiliations: Department of Nutrition,
Harvard School of Public Health, Boston, Mass.
In a 1981 landmark report, Doll and Peto1 estimated
that 35% of US cancer deaths were attributable to dietary factors. This estimate
was primarily based on the large differences in rates of specific cancers
among countries and observations that these rates were strongly correlated
with aspects of national food supplies. However, these authors acknowledged
major uncertainties in responsible aspects of diet and the magnitude of impact.
Willett WC. Diet and CancerAn Evolving Picture. JAMA. 2005;293(2):233-234. doi:10.1001/jama.293.2.233