In Reply: Thank you to all who responded to
the joint editorial published by the ICMJE. I respond only for myself to the
3 authors whose representative letters appear in this issue of JAMA.
Ms Dresser addresses the advantage of a comprehensive trial registry
in raising public awareness that the purpose of clinical research is to advance
knowledge, not to provide the best treatment for participants. I submit that
the raised public awareness and the occasional successful treatment of patients
who volunteer for such studies are both secondary but welcome outcomes of
a clinical trial registry.
DeAngelis CD. Clinical Trial Registration and the ICMJE—Reply. JAMA. 2005;293(2):157-158. doi:10.1001/jama.293.2.158-a