Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: In their article on the effects
of antihypertensive agents on cardiovascular events in patients with coronary
disease and normal blood pressure, Dr Nissen and colleagues1 found
that the amlodipine group had both a significant decrease in cardiovascular
events and a slower progression of coronary atherosclerosis as assessed by
intravenous ultrasound (IVUS). We have some concerns about the study.
Aboyans V, Lacroix P, Cassat C. Antihypertensive Agents and Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure. JAMA. 2005;293(10):1187-1189. doi:10.1001/jama.293.10.1187-a