Most people know consuming fatty foods can have negative health effects.
Now, researchers studying rats and mice have identified the molecular mechanism
by which saturated and trans-fats trigger a rise
in blood cholesterol and triglycerides, increasing the risk of cardiovascular
disease (Lin et al. Cell. 2005;120:261-273).
The molecular players in this scenario are also found in humans. Although
it remains to be seen whether the results will have clinical relevance, pharmaceutical
companies have already expressed interest in the implications of the new findings
for treating individuals with elevated blood cholesterol levels.
Hampton T. Molecular Switch Triggers Fats’ Harm. JAMA. 2005;293(10):1180. doi:10.1001/jama.293.10.1180