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March 16, 2005

Pegylated Interferon vs Standard Interferon for Chronic Hepatitis C

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;293(11):1323-1324. doi:10.1001/jama.293.11.1323-a

To the Editor: Dr Carrat and colleagues1 compared ribavirin combined with either pegylated interferon or standard interferon for treatment of hepatitis C in patients infected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Their results are consistent with previous studies in HIV-seronegative persons, which showed that viral load reduction correlates with improvement in hepatic function.2 However, there are 2 issues I would like to address.

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