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March 23/30, 2005

ABO Blood Group and Susceptibility to Severe Acute Respiratory Syndrome

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;293(12):1447-1451. doi:10.1001/jama.293.12.1450-c

To the Editor: ABO blood group has been reported to influence susceptibility to the Norwalk virus and Helicobacter pylori infections.1,2 The prevalence of H pylori infection in Taiwan is significantly higher in patients with blood group O than in those with other blood groups,3 possibly due to a reduced number of H pylori receptors in persons with group A or group B blood. We studied the relationship between ABO blood group and the development of severe acute respiratory syndrome coronavirus (SARS-CoV) infection in a group of health care workers who were exposed to an index SARS patient and who were not wearing any personal protective equipment.

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