ROBERT T. LEGGE, PH.G., M.D. MCCLOUD, CAL.
During the summer of 1903 I had occasion to treat a family with Diphtheria;
one patient died from the laryngeal form after tracheotomy had been performed
and large doses of antitoxin had been administered. An aunt acted as a nurse;
she has exophthalmic goiter, with all the classic symptoms. No immunizing
dose of antitoxin was given her, and she was infected with moderately severe
pharyngeal diphtheria. I immediately injected 1,500 units of antitoxin and
repeated the dose on the following day, combined with local antiseptic and
internal supportive treatment, with the result that at the end of the week
she was convalescent.
DIPHTHERIA ANTITOXIN IN THE TREATMENT OF GOITER.. JAMA. 2005;293(15):1854. doi:10.1001/jama.293.15.1854