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April 20, 2005

Drug-Eluting Stents and In-Stent Restenosis

JAMA. 2005;293(15):1855-1856. doi:10.1001/jama.293.15.1855-a

To the Editor: From a practical standpoint, detailing the logistics required to administer the 600-mg clopidogrel pretreatment 2 hours before intervention, as was done in the study by Dr Kastrati and colleagues,1 will be helpful, considering that in most centers patients with in-stent restenosis undergo ad hoc reintervention, and only complex cases are scheduled for staged procedures. In addition, it would be valuable to identify potential predictors of drug-eluting stent failure to provide early triage and, eventually, to divert patients to alternative techniques.24

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