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Clinical Crossroads Update
April 27, 2005

A 50-Year-Old Man With Hepatitis C and Cirrhosis Needing Liver Transplantation, 18 Months Later

JAMA. 2005;293(16):2027. doi:10.1001/jama.293.16.2027

In a Clinical Crossroads held at Medicine Grand Rounds in March 2003, Dr Douglas Hanto discussed the case of Mr G, a 50-year-old man needing liver transplantation.1 Mr G had hepatitis C and cirrhosis and had been treated with ribavirin and interferon unsuccessfully. He had 2 episodes of bleeding from esophageal varices and had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure. At the time of the conference, Mr G was receiving disability due to significant fatigue, difficulty concentrating, and poor memory. His model end-stage liver disease (MELD) score was 18.

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