In a Clinical Crossroads held at Medicine Grand Rounds in March 2003,
Dr Douglas Hanto discussed the case of Mr G, a 50-year-old man needing liver
transplantation.1 Mr G had hepatitis C and
cirrhosis and had been treated with ribavirin and interferon unsuccessfully.
He had 2 episodes of bleeding from esophageal varices and had undergone a
transjugular intrahepatic portosystemic shunt (TIPS) procedure. At the time
of the conference, Mr G was receiving disability due to significant fatigue,
difficulty concentrating, and poor memory. His model end-stage liver disease
(MELD) score was 18.
Ship AN. A 50-Year-Old Man With Hepatitis C and Cirrhosis Needing Liver Transplantation, 18 Months Later. JAMA. 2005;293(16):2027. doi:10.1001/jama.293.16.2027