Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
In Reply: Dr Goldstein raises concern over
the use of nicotinic acid (niacin) in the acute management of patients with
non–ST-segment elevation acute coronary syndromes. This is based on
a case report from 1991 that describes worsened ischemia in 2 patients with
unstable angina following the administration of crystalline niacin.1 We are aware of no other similar reports.
Gluckman TJ, Sachdev M, Schulman SP, Blumenthal RS. Use of Niacin During Non–ST-Segment Elevation Acute Coronary Syndromes—Reply. JAMA. 2005;293(17):2092-2093. doi:10.1001/jama.293.17.2093