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Medical News and Perspectives
May 4, 2005

Reducing HIV Vertical Transmission Scrutinized

JAMA. 2005;293(17):2079-2081. doi:10.1001/jama.293.17.2079

Boston—Although anti-HIV drug regimens have had a profound impact on preventing mother-to-child transmission of HIV, researchers have been grappling with the potential health consequences of a treatment strategy commonly used in resource-poor countries for that purpose. Findings presented here at the 12th Annual Retrovirus Conference provide new evidence regarding some potential risks of this regimen—which consisted of a single dose of nevirapine during labor to the mother and a single dose to the newborn during the first 3 days after delivery—as well as some early evidence showing potential benefits from alternative regimens.

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