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May 11, 2005

Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;293(18):2211-2212. doi:10.1001/jama.293.18.2212-a

To the Editor: The Clinical Review by Dr Sink and colleagues1 erroneously presents the results of one of the cited studies.2 On page 602, the article states “ . . . the intention-to-treat analysis found only the 16-mg/d dose to be significantly better than placebo . . . with no benefit for the other doses,” using the Neuropsychiatric Inventory as the outcome. In fact, both the 16-mg/d and the 24-mg/d galantamine doses were found to be significantly better than placebo for the Neuropsychiatric Inventory as well as for all other outcome measures.2

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