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Medical News and Perspectives
May 11, 2005

The Gut Yields Clues to Obesity, Therapies

JAMA. 2005;293(18):2200-2201. doi:10.1001/jama.293.18.2200

The way to solving the obesity problem may be through the gut, or at least through the hormones that emanate from it, according to evidence about the crucial role gut hormones play in regulating appetite and body weight.

In a review summarizing 20 years of research on gut hormones, researchers highlight the role of such hormones in maintaining energy balance and how they might be exploited for the development of obesity treatments (Badman and Flier. Science. 2005;307:1909-1911). This organ, research has revealed, has a highly redundant system of endocrine and neurological signals.

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