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June 8, 2005

Multidrug-Resistant TuberculosisNews From the Front

Author Affiliations

Author Affiliation: Department of Medicine, Michigan State University, East Lansing.

JAMA. 2005;293(22):2788-2790. doi:10.1001/jama.293.22.2788

During the past decade, multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid and rifampin, has declined in the United States.1 The number of reported MDR-TB cases has decreased from 486 in 1993 to 114 in 2003, and the proportion of resistant strains of Mycobacterium tuberculosis has decreased by half.1 The decline is heartening but this issue of JAMA includes 2 reports from California and Russia showing why celebration would be premature.2,3

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