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Health Agencies Update
June 22/29, 2005

New Combination Vaccine

JAMA. 2005;293(24):2992. doi:10.1001/jama.293.24.2992-a

The first combination booster vaccine against pertussis, tetanus, and diphtheria for adolescents has been approved by the Food and Drug Administration. It will be marketed as Boostrix by GlaxoSmithKline Inc (Brentford, Middlesex, England) and indicated for use as a single booster dose to adolescents aged 10 to 18 years.

Although combination booster vaccines exist against tetanus and diphtheria, this is the first to include pertussis, a highly communicable disease that can be particularly serious for infants. The disease is usually less severe in adolescents, but they may transmit it to susceptible infants and other family members. In the last 20 years, rates of pertussis infection have been increasing.

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