Author Affiliation: Duke University Medical
Center, Durham, NC.
Physicians should always strive to optimize the form and intensity of
interventions used in medical care and to find an ideal strategy that maximizes
therapeutic benefits while minimizing adverse consequences and costs. With
regard to pharmacological intervention, optimization of process is usually
accomplished by comparison of varying drug combinations and drug doses in
formal randomized clinical trials. In a similar manner, quality improvement
(QI) interventions should also be tested and optimized through rigorously
designed evaluations. And, as with drug therapy, it is important to define
the form of intervention and the intensity required to effectively and efficiently
improve care practices.
Peterson ED. Optimizing the Science of Quality Improvement. JAMA. 2005;294(3):369-371. doi:10.1001/jama.294.3.369