With the goal of understanding and manipulating the behavior of cells
gone awry, many cancer researchers have turned to the gene-silencing technique
known as RNA interference with the hope of using the approach to effectively
mute the expression of genes that drive malignancies. Now, three new studies
in the June 9 issue of Nature point to naturally
occurring roles of interfering RNAs called microRNAs in cancer development,
findings that could one day lead to new diagnostics and therapies.
Hampton T. MicroRNAs Move Into Cancer Research. JAMA. 2005;294(4):411-412. doi:10.1001/jama.294.4.411