Author Affiliations: Department of Cardiology,
Columbus and San Raffaele Hospitals, Milan, Italy.
Percutaneous coronary interventions (PCIs) have become the dominant
form of revascularization. This evolution has been based on the results of
a large number of pivotal randomized trials. Since the pioneering work of
Gruntzig,1 2 major developments have revolutionized
clinical cardiology practice. The first was the introduction of bare metal
stents by Sigwart and Puel in 1986 and results following use of stents to
treat impending or acute vessel closure after balloon angioplasty were subsequently
reported in 1987.2 Stent implantation improved
both acute and long-term results following angioplasty, but perhaps more important
from the patient’s perspective, dramatically reduced the need for emergency
coronary artery bypass graft (CABG) surgery.
Colombo A, Cosgrave J. Paclitaxel-Eluting Stents in Complex Lesions. JAMA. 2005;294(10):1268-1270. doi:10.1001/jama.294.10.1268