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September 14, 2005

Paclitaxel-Eluting Stents in Complex Lesions

Author Affiliations

Author Affiliations: Department of Cardiology, Columbus and San Raffaele Hospitals, Milan, Italy.

JAMA. 2005;294(10):1268-1270. doi:10.1001/jama.294.10.1268

Percutaneous coronary interventions (PCIs) have become the dominant form of revascularization. This evolution has been based on the results of a large number of pivotal randomized trials. Since the pioneering work of Gruntzig,1 2 major developments have revolutionized clinical cardiology practice. The first was the introduction of bare metal stents by Sigwart and Puel in 1986 and results following use of stents to treat impending or acute vessel closure after balloon angioplasty were subsequently reported in 1987.2 Stent implantation improved both acute and long-term results following angioplasty, but perhaps more important from the patient’s perspective, dramatically reduced the need for emergency coronary artery bypass graft (CABG) surgery.

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