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September 28, 2005

Identification of Potential Multitarget Antimalarial Drugs

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(12):1487-1491. doi:10.1001/jama.294.12.1490

To the Editor: Malaria is one of the deadliest tropical diseases, causing more than 300 million infections yearly.1 Successful clearance of the malarial parasites, Plasmodium species, from a patient’s body by antimalarial drugs is impeded by the emergence of drug-resistant strains. Drugs that effectively eliminate Plasmodium with short treatment duration reduce risk of treatment failure and emergence of drug-resistant strains.1

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