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Letters
September 28, 2005

Single-Donor Islet Transplantation for Diabetes—Reply

Author Affiliations
 

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(12):1488-1489. doi:10.1001/jama.294.12.1488-b

In Reply: Achieving and maintaining insulin independence in the majority of recipients with diabetes after their first single-donor islet transplant will be critical to increasing the availability of islet transplants. Otherwise, many fewer candidates for islet transplantation can actually receive a transplant than the donor pool would otherwise allow. We agree with Dr Smith about “using as many donors as possible to treat as many patients as possible” but not as many as are necessary to achieve insulin independence. An inefficient use of donors will hinder the implementation of islet transplantation into health care delivery systems.

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