Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
In Reply: Achieving and maintaining insulin
independence in the majority of recipients with diabetes after their first
single-donor islet transplant will be critical to increasing the availability
of islet transplants. Otherwise, many fewer candidates for islet transplantation
can actually receive a transplant than the donor pool would otherwise allow.
We agree with Dr Smith about “using as many donors as possible to treat
as many patients as possible” but not as many as are necessary to achieve
insulin independence. An inefficient use of donors will hinder the implementation
of islet transplantation into health care delivery systems.
Hering BJ, Sutherland DER. Single-Donor Islet Transplantation for Diabetes—Reply. JAMA. 2005;294(12):1488-1489. doi:10.1001/jama.294.12.1488-b