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September 28, 2005

Clinical Factors and Recurrent Venous Thrombotic Events—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(12):1489-1490. doi:10.1001/jama.294.12.1489-b

In Reply: We followed up 474 patients with a first deep vein thrombosis for a mean (SD) of 7.3 (2.7) years and found a recurrence rate of 25.9 per 1000 patient-years—33.2 per 1000 patient-years for those with an idiopathic first thrombotic event and 17.7 per 1000 patient-years for those with a provoked first thrombotic event. Of all 90 recurrences, 61 were idiopathic and 29 were provoked (defined as pregnancy, puerperium, use of oral contraceptives within 30 days, or trauma, surgery, immobilization, or use of plaster casts within 3 months before the event).

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