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October 26, 2011

Bronchoalveolar Lavage–Directed Therapy in Children With Cystic Fibrosis and Pseudomonas aeruginosa Infection

Author Affiliations

Author Affiliations: Mid-Western Regional Hospital, Limerick, Ireland (Dr Linnane) (barry.linnane@hse.ie); and Our Lady's Children's Hospital Crumlin, Dublin, Ireland (Dr McNally).

JAMA. 2011;306(16):1761-1762. doi:10.1001/jama.2011.1518

To the Editor: The study by Dr Wainwright and colleagues on the effect of bronchoalveolar lavage (BAL)–directed therapy in children with cystic fibrosis on Pseudomonas aeruginosa infection and chest computed tomography (CT) findings at 5 years of age1 was not appropriately designed to explore the true utility of BAL in preschool children with cystic fibrosis. We believe there is a flaw in the premise of the study.

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