Letters Section Editor: Robert M. Golub, MD, Senior Editor.
In Reply: Drs Branco and Garcia suggest that the prone position should be evaluated further in children with acute lung injury despite the negative results of our randomized clinical trial. It is true that there was an improvement in the OI in our study in patients treated with prone positioning, but this was not associated with an improvement in the duration of ventilation or mortality. Several clinical studies have shown that an improvement in oxygenation does not necessarily correlate with improvements in clinical outcomes.1- 3
Curley MAQ, Hibberd PL, Barr FE, Cvijanovich NZ, Matthay MA, Arnold JH. Prone Positioning in Children With Acute Lung Injury—Reply. JAMA. 2005;294(18):2297-2298. doi:10.1001/jama.294.18.2297-b